Título : "Molecular and cell biological investigations into pattern formation of the human parasite Echinococcus multilocularis"
Disertante: Master in Science Luisa Schiegl - University of Wuerzburg, Germany
Director: Prof. Dr. Klaus Brehm
Codirector: Prof. Dr. Christian Janzen
Resumen
The lethal zoonosis Alveolar echinococcosis (AE) is prevalent in the Northern Hemisphere and is caused by the infiltrative growth of the metacestode larval stage of the fox tapeworm Echinococcus multilocularis. The tumor-like development of the metacestode is stem cell driven and results from Wnt/b-Catenin signaling modifying body axis formation. However, given the complexity of these processes, it is likely that additional conserved signaling pathways contribute to the regulation of parasite proliferation and differentiation. Known as a regulator of the organ size in metazoans, the Hippo signaling pathway has been identified and characterized in E. multilocularis in this study.
Los esperamos el próximo martes 13 de mayo a las 12.30 h en el aula del Piso 13 de la Facultad de Medicina - UBA.
